World No. 12 · 109 career titles · career win–loss 1568–417. Match history, ranking timeline and head-to-head records below.

| Country | Serbia |
| Born | 1987 |
| Plays | 右利き |
| Backhand | двуручный |
| Height | 188 cm |
| Win–loss | 1568–417 |
| Titles | 109 |
| Grand Slam titles | 24 |
| Masters 1000 | 40 |
| Finals | 45 |
| Ranking | #12 · 2 980 ポイント |
| Career high | #1 |
Strength 0–100 is our own calculation, not an official tour ranking: 100 is the strongest in history, 70 is about the level of the world No. 100.
| Event · Round | Opponent | Score | Surface | |
|---|---|---|---|---|
| L | US Open · R128 | Mariano Navone (ARG) | 7-6, 5-7, 4-6, 6-2, 6-1 | Hard |
| L | US Open · R16 | Aryna Sabalenka (BLR) | 1-4, 4-2, 1-0(2) | |
| L | Cincinnati Open · R64 | Thiago Agustin Tirante (ARG) | 2-6, 6-4, 6-4 | Hard |
| W | Wimbledon · QF | Felix Auger Aliassime (CAN) | 7-6, 3-6, 6-3, 6-7, 7-6 | Grass |
| W | Wimbledon · R64 | Stefanos Tsitsipas (GRE) | 6-3, 6-4, 6-2 | Grass |
| L | Wimbledon · SF | Jannik Sinner (ITA) | 6-4, 6-4, 6-4 | Grass |
| W | Wimbledon · R16 | Roman Safiullin (RUS) | 7-6, 6-3, 3-6, 6-3 | Grass |
| W | Wimbledon · R32 | Arthur Rinderknech (FRA) | 7-5, 6-4, 1-6, 7-6 | Grass |
| W | Wimbledon · R128 | Yibing WU | 6-4, 5-7, 6-4, 6-4 | |
| W | Wimbledon · R128 | Yibing Wu | 6-4, 5-7, 6-4, 6-4 | Grass |
| L | Roland Garros · R32 | Joao Fonseca | 4-6, 4-6, 6-3, 7-5, 7-5 | Clay |
| L | French Open · R32 | Joao Fonseca | 4-6, 4-6, 6-3, 7-5, 7-5 |
| Season | Win–Loss | Titles | Year-end rank |
|---|---|---|---|
| 2026 | 19–10 | ||
| 2025 | 44–14 | 2 | |
| 2024 | 43–11 | 1 | |
| 2023 | 63–15 | 7 | |
| 2022 | 50–13 | 5 | |
| 2021 | 78–17 | 6 | |
| 2020 | 68–9 | 6 | |
| 2019 | 92–27 | 5 | |
| 2018 | 93–25 | 4 | |
| 2017 | 67–17 | 2 | |
| 2016 | 93–16 | 7 | |
| 2015 | 92–11 | 11 |